Researcher (collaboration)
Hobby: photography, travelling, progressive rock
Publications:
Enzymatically cleavable traceless biotin tags for protein PEGylation and purification
Adam M. Wawro, Yusuke Aoki, Takahiro Muraoka, Kouhei Tsumoto and Kazushi Kinbara
Chem. Commun., 2018, 54, 1913–1916 (10.1039/C7CC05814D).
Newly characterized interaction stabilizes DNA structure: oligoethylene glycols stabilize G-quadruplexes CH–π interactions
Hisae Tateishi-Karimata, Tatsuya Ohyama, Takahiro Muraoka, Peter Podbevsek, Adam M. Wawro, Shigenori Tanaka, Shu-ichi Nakano, Kazushi Kinbara, Janez Plavec, and Naoki Sugimoto
Nucleic Acids Res. 2017, 45, 7021–7030.
DOI: 10.1093/nar/gkx299
Multigram chromatography-free synthesis of octa(ethylene glycol) p-toluenesulfonate
Adam M. Wawro, Takahiro Muraoka, Maho Kato, and Kazushi Kinbara
Org. Chem. Front. 2016, 3, 1524–1534.
DOI: 10.1039/C6QO00398B
Chromatography-Free Synthesis of Monodisperse Oligo(ethylene glycol) Mono-p-toluenesulfonates and Quantitative Analysis of Oligomer Purity
Adam. M. Wawro, Takahiro Muraoka, and Kazushi Kinbara
Polym. Chem. 2016, 7, 2389–2394.
DOI: 10.1039/C6PY00127K
Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties
Paweł Borowiecki, Adam M. Wawro, Patrycja Wińska, Monika Wielechowska, Maria Bretner
Eur. J. Med. Chem. 2014, 84, 364–374
DOI: 10.1016/j.ejmech.2014.07.019
Synthesis of new optically pure tetrabromobenzotriazole derivatives via lipase-catalyzed transesterification
Adam M. Wawro, Monika Wielechowska and Maria Bretner
J. Mol. Catal. B Enzym. 2013, 87, 44–50.
DOI: 10.1016/j.molcatb.2012.10.013
Patents:
WO 2017002853; JP 2017014371
Inventors: Kazushi Kinbara, Takahiro Muraoka, Adam M. Wawro (Tohoku University), Tomoyuki Ohtake, Eui-Chul Kang, Tomoki Uruga, Ryutaro Imamura (NOF Corporation)
Presentations:
International Conference Presentations:
2015, November: The 16th Tetrahedron Symposium Asia Edition (Shanghai, China)
“Monodisperse PEG derivatives: straightforward synthesis and analysis revisited”
Adam M. Wawro, Takahiro Muraoka, Kazushi Kinbara
(poster)
2014, December: The 10th SPSJ International Polymer Conference (Tsukuba, Japan)
“Development of amphiphilic oligo(ethylene glycol)s with geometric structures”
Adam M. Wawro, Takahiro Muraoka, Kazushi Kinbara
(poster)
2013, December: The 12th International Conference on Frontiers of Polymers and Advanced Materials (Auckland, New Zealand)
“Non-linear amphiphilic discrete oligo(ethylene glycol)s: synthesis and protein modification”
Adam M. Wawro, Takahiro Muraoka, Mihoko Ui, Kazushi Kinbara
(poster)
2012, June: The 13th Tetrahedron Symposium (Amsterdam, The Netherlands)
“Enzyme-catalyzed separation of optically pure 4,5,6,7-tetrabromo-1H-benzotriazole derivatives, potential inhibitors of CK2 kinase”
Maria Bretner, Adam M. Wawro, Monika Wielechowska
(poster)
2011, November: Eurobiotech 2011 (Cracow, Poland)
“Synthesis of optically pure tetrabromobenzotriazole derivatives via lipase-catalyzed reactions as potential CK2 kinase inhibitors”
Adam M. Wawro, Monika Wielechowska, Maria Bretner
(poster)
Domestic Conference Presentations:
2016, May: 71th Symposium of the Society of Synthetic Organic Chemistry, Kanto branch (Tokyo, Japan)
“Chromatography-free strategy for synthesis of monodisperse PEG monotosylates”
Adam M. Wawro, Takahiro Muraoka, Kazushi Kinbara
(oral)
2015, September: 64th SPSJ Symposium on Macromolecules (Sendai, Japan)
“Towards simplicity in synthesis of monodisperse PEG derivatives”
Adam M. Wawro, Takahiro Muraoka, Kazushi Kinbara
(oral)
2014, June: 25th Banyu Sendai Symposium (Sendai, Japan)
“Monodispersed PEG: building block for functional amphiphilic molecules”
Adam M. Wawro, Takahiro Muraoka, Kazushi Kinbara
(poster)
2014, March: Chemical Society of Japan Annual Meeting (Nagoya, Japan)
“Amphiphilic derivatives of oligo(ethylene glycol)s: development and characterization”
Adam M. Wawro, Takahiro Muraoka, Kazushi Kinbara
(poster)